Serious Mental Illness App Research Case Study
What a fully remote randomized trial suggests about mobile support across bipolar disorder, major depression, and schizophrenia-spectrum conditions.
This page summarizes the CORE serious mental illness study in plain language. It is especially important to frame this as adjunctive support, not a replacement for psychiatric care.
Remote app support across serious mental illness groups.
The CORE study was a fully remote waitlist-controlled randomized trial involving participants from 45 US states.
The study reached a broad remote sample.
Ben-Zeev et al. (2021) included 315 participants from 45 US states, showing that this type of mobile mental health research can be conducted remotely at meaningful scale.
The proposal notes baseline diagnostic breakdown: bipolar 35.2%, major depression 43.2%, and schizophrenia or schizoaffective disorder 21.6%.
1. A fully remote RCT tested the CORE intervention.
The study used a remote waitlist-controlled randomized design with baseline, 30-day, and 60-day assessments.
2. The sample included several serious mental illness groups.
Participants included people with bipolar disorder, major depression, and schizophrenia-spectrum conditions.
| Paper | Year | What it contributes |
|---|---|---|
| Ben-Zeev et al. – CORE Serious Mental Illness doi.org/10.2196/29201 |
2021 | 315 participants from 45 US states; remote waitlist-controlled RCT across bipolar, major depression, and schizophrenia-spectrum conditions. |
This page should emphasize adjunctive support.
Because the conditions are high-acuity, the page should be careful and practical. The research supports remote digital mental health support, but visitors should not read it as a replacement for psychiatric or crisis care.
Use alongside appropriate clinical care.
Visitors can explore app-based support while maintaining care plans, medication management, or clinician guidance where relevant.